diff --git a/src/qt/checklst.cpp b/src/qt/checklst.cpp
index 3411ef59f6..255dc0a65b 100644
--- a/src/qt/checklst.cpp
+++ b/src/qt/checklst.cpp
@@ -80,8 +80,13 @@ bool wxCheckListBox::IsChecked(unsigned int n) const
 
 void wxCheckListBox::Check(unsigned int n, bool check )
 {
+    // Prevent the emission of wxEVT_CHECKLISTBOX event by temporarily block all
+    // signals on m_qtListWidget object. QSignalBlocker can be used instead when
+    // Qt 5.3 becomes the minimum supprted version.
+    const bool wasBlocked = m_qtListWidget->blockSignals(true);
     QListWidgetItem* item = m_qtListWidget->item(n);
     wxCHECK_RET(item != nullptr, wxT("wrong listbox index") );
-    return item->setCheckState(check ? Qt::Checked : Qt::Unchecked);
+    item->setCheckState(check ? Qt::Checked : Qt::Unchecked);
+    m_qtListWidget->blockSignals(wasBlocked);
 }